PRRT2

Across TCGA patient cohorts, PRRT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,423 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PRRT2-associated proteins across cancer lineages are MVP, RABEP2, and SERBP1. Each is linked with PRRT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRRT2-to-partner and partner-to-PRRT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRT2 versus MVP in CCRCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT2→partner) and Y-score (partner→PRRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MVP →	+0.386	+0.406	.003	<.001	3	5
BRCA	RABEP2 →	+0.312	+0.975	<.001	<.001	3	4
HNSC	SERBP1 →	-0.257	-0.526	<.001	.006	2	5
BRCA	RPSA →	-0.159	-0.845	<.001	<.001	3	4
BRCA	SHMT2 →	-0.568	-0.882	<.001	.002	3	4
BRCA	MICALL1 →	-0.326	-0.843	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,423 associations by consensus.

PRRT2 vs MVP — CCRCC

Explore this scatter interactively →