PRRT1B

Across TCGA cell cohorts, PRRT1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,501 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible PRRT1B-associated GO terms across cancer lineages are Renal D-glucose absorption, Copper ion export, and Serotonin receptor signaling pathway. Each is linked with PRRT1B in more than 7 cancer types. Because this analysis shows association rather than direction, both PRRT1B-to-partner and partner-to-PRRT1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal D-glucose absorption grouped by PRRT1B-low versus PRRT1B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT1B→partner) and Y-score (partner→PRRT1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Renal D-glucose absorption →	+2.249	+2.375	<.001	<.001	3	8
OVARY	Copper ion export →	-0.143	-0.369	<.001	.005	3	8
BREAST	Serotonin receptor signaling pathway →	+0.302	+1.413	<.001	<.001	3	7
BREAST	Regulation of calcium ion import across plasma membrane →	-0.181	-1.835	<.001	<.001	3	7
LIVER	Trans-synaptic signaling by BDNF, modulating synaptic transmission →	-1.393	-2.035	.005	.005	3	7
LIVER	Trans-synaptic signaling by BDNF →	-1.393	-2.035	.005	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,501 associations by consensus.

Renal D-glucose absorption by PRRT1B expression — LIVER

Explore this box plot interactively →