Across TCGA patient cohorts, PRRT1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,502 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRRT1-associated genes across cancer lineages are SLC16A8, RASL10A, and NEFH. Each is linked with PRRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRRT1-to-partner and partner-to-PRRT1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRT1→partner) and Y-score (partner→PRRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC16A8 →	+0.672	+0.488	<.001	<.001	3	1
GBM	RASL10A →	+0.954	+0.526	<.001	<.001	3	1
GBM	NEFH →	+1.361	+0.660	<.001	<.001	3	1
GBM	RASD2 →	+0.582	+0.516	.002	<.001	3	1
GBM	SYNGR1 →	+0.930	+0.544	<.001	<.001	3	1
GBM	PNPLA5 →	+0.315	+0.612	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

Exploration

PRRT1 survival (RNA) · tumor vs normal (RNA) · all PRRT1 data types