PRRG3

Across TCGA patient cohorts, PRRG3 protein abundance is significantly associated with the RNA expression of many other genes, with 1,455 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRRG3-associated genes across cancer lineages are ATP1B1, NOP53, and RPS6. Each is linked with PRRG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRRG3-to-partner and partner-to-PRRG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRG3 versus ATP1B1 in LSCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRG3→partner) and Y-score (partner→PRRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ATP1B1 →	+1.429	+1.425	<.001	.008	3	2
LUAD	NOP53 →	+0.910	+1.200	.007	.009	3	1
LUAD	RPS6 →	+1.067	+1.080	.002	.002	3	1
LUAD	MIR183 →	+0.962	+0.876	<.001	.002	3	1
LUAD	CLRN2 →	+0.122	+1.607	<.001	.007	3	1
LSCC	TOP3B →	+0.351	+1.614	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,455 associations by consensus.

PRRG3 vs ATP1B1 — LSCC

Explore this scatter interactively →