PRRG3

Across TCGA cell cohorts, PRRG3 mutation is significantly associated with the mutation status of many other genes, with 2,107 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRRG3-associated genes across cancer lineages are KAT2B, MYH10, and INHBE. Each is linked with PRRG3 in more than 2 cancer types. Because this analysis shows association rather than direction, both PRRG3-to-partner and partner-to-PRRG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KAT2B grouped by PRRG3-low versus PRRG3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRG3→partner) and Y-score (partner→PRRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KAT2B →	+5.014	+5.584	.003	.003	1	3
BLOOD_Leukemia	MYH10 →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	INHBE →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	POGZ →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	DUSP10 →	+6.321	+6.321	.001	.001	1	3
BLOOD_Leukemia	WWC2 →	+4.321	+5.285	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,107 associations by consensus.

KAT2B by PRRG3 expression — BLOOD_Lymphoma

Explore this box plot interactively →