PRRG1

Across TCGA patient cohorts, PRRG1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,552 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PRRG1-associated genes across cancer lineages are E2F3, RPS27AP9, and MRPS34. Each is linked with PRRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRRG1-to-partner and partner-to-PRRG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRRG1 versus E2F3 in GBM, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRG1→partner) and Y-score (partner→PRRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	E2F3 →	-0.592	-0.817	.003	.004	3	2
CCRCC	RPS27AP9 →	-0.679	-0.524	<.001	<.001	3	2
BRCA	MRPS34 →	-0.729	-2.004	.003	.002	3	2
GBM	YY1 →	-0.208	-0.647	.002	.001	3	1
GBM	CTCF →	-0.307	-0.728	.004	.003	3	1
GBM	GSPT1 →	-0.223	-0.689	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,552 associations by consensus.

PRRG1 vs E2F3 — GBM

Explore this scatter interactively →