PRRG1

Across TCGA cell cohorts, PRRG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,547 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRRG1-associated GO terms across cancer lineages are Negative regulation of lymphocyte activation, Maintenance of protein location, and Viral process. Each is linked with PRRG1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PRRG1-to-partner and partner-to-PRRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lymphocyte activation grouped by PRRG1-low versus PRRG1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRRG1→partner) and Y-score (partner→PRRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of lymphocyte activation →	+0.080	+1.072	<.001	<.001	3	11
LIVER	Maintenance of protein location →	+0.154	+1.617	<.001	.002	3	10
BREAST	Viral process →	+0.092	+1.348	<.001	<.001	3	10
BREAST	Biological process involved in symbiotic interaction →	+0.108	+1.517	<.001	<.001	3	10
LIVER	Maintenance of protein location in cell →	+0.155	+1.617	<.001	.002	3	9
BREAST	Positive regulation of viral process →	+0.073	+1.057	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,547 associations by consensus.

Negative regulation of lymphocyte activation by PRRG1 expression — BREAST

Explore this box plot interactively →