PRR7

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, PRR7 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated PRR7 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher PRR7 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated PRR7 expression acts as an unfavorable survival marker.

CESC are the cancer types where PRR7 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSMedianAll0.0680.875<.00136view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

PRR7–CESC (OS)

Kaplan–Meier survival curve for PRR7 mutant vs wild-type samples in CESC.

Open the CESC breakdown →

Exploration