PRR5L

Across TCGA patient cohorts, PRR5L protein abundance is significantly associated with the RNA expression of many other genes, with 2,932 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRR5L-associated genes across cancer lineages are ADAM19, MMP13, and ADAMTS2. Each is linked with PRR5L in more than 2 cancer types. Because this analysis shows association rather than direction, both PRR5L-to-partner and partner-to-PRR5L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRR5L versus ADAM19 in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR5L→partner) and Y-score (partner→PRR5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ADAM19 →	+1.357	+0.589	<.001	<.001	3	3
BRCA	MMP13 →	+2.569	+0.393	<.001	.001	3	3
BRCA	ADAMTS2 →	+1.799	+0.573	<.001	.001	3	3
BRCA	SERPINB9 →	+1.139	+0.447	<.001	.009	3	3
BRCA	MIR22HG →	+0.987	+0.554	<.001	.002	3	3
OV	LRIG3 →	+1.244	+0.774	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,932 associations by consensus.

PRR5L vs ADAM19 — BRCA

Explore this scatter interactively →