PRR5L

Across TCGA cell cohorts, PRR5L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,636 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRR5L-associated GO terms across cancer lineages are Integrin-mediated signaling pathway, Angiogenesis, and Response to hypoxia. Each is linked with PRR5L in more than 8 cancer types. Because this analysis shows association rather than direction, both PRR5L-to-partner and partner-to-PRR5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Integrin-mediated signaling pathway grouped by PRR5L-low versus PRR5L-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR5L→partner) and Y-score (partner→PRR5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Integrin-mediated signaling pathway →	+0.140	+1.228	<.001	<.001	3	9
BREAST	Angiogenesis →	+0.116	+1.803	<.001	<.001	3	9
OVARY	Response to hypoxia →	+0.065	+1.605	<.001	.004	3	9
SOFT_TISSUE	Negative regulation of pre-miRNA processing →	-0.840	-1.691	<.001	<.001	3	9
BREAST	CD8-positive, alpha-beta T cell activation →	+0.122	+1.100	<.001	<.001	3	9
BREAST	Regulation of fibroblast proliferation →	+0.088	+1.399	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,636 associations by consensus.

Integrin-mediated signaling pathway by PRR5L expression — BREAST

Explore this box plot interactively →