PRR5L

Across TCGA cell cohorts, PRR5L mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible PRR5L-associated genes across cancer lineages are SULT1C3 and MS4A18. Each is linked with PRR5L in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR5L-to-partner and partner-to-PRR5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SULT1C3 grouped by PRR5L-low versus PRR5L-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR5L→partner) and Y-score (partner→PRR5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	SULT1C3 →	+0.192	+5.196	<.001	.005	3	1
OVARY	MS4A18 →	+0.013	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SULT1C3 by PRR5L expression — OVARY

Explore this box plot interactively →