Across TCGA pan-cancer cohorts, PRR5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated PRR5 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher PRR5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PRR5 expression acts as an unfavorable survival marker.

LSCC, LUAD, and HNSC are the cancer types where PRR5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	0.724	0.961	.008	22	view →
LUAD	DFS	Quartile	II,III,IV	0.384	1.000	.024	13	view →
HNSC	OS	Tertile	II,III,IV	0.799	0.955	.038	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: PRR5 tumor-vs-normal RNA expression · all PRR5 data types