Across TCGA patient cohorts, PRR5 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,114 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRR5-associated proteins across cancer lineages are KANK2, PRR5_S240, and SNF8. Each is linked with PRR5 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRR5-to-partner and partner-to-PRR5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR5→partner) and Y-score (partner→PRR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KANK2 →	+0.343	+0.481	<.001	<.001	3	4
LUAD	PRR5_S240 →	+0.769	+0.380	<.001	<.001	3	4
LSCC	SNF8 →	+0.211	+0.448	.001	.004	3	4
LSCC	ACAP2 →	+0.463	+0.625	<.001	<.001	3	3
PDAC	TLN2 →	+0.315	+0.346	<.001	<.001	3	3
PDAC	MAP1A_S1172 →	+0.645	+0.270	.002	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,114 associations by consensus.

Exploration

PRR5 survival (RNA) · tumor vs normal (RNA) · all PRR5 data types