Across TCGA patient cohorts, PRR5 mutation is significantly associated with the RNA expression of many other genes, with 181 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR5-associated genes across cancer lineages are MTND5P7, NDUFS6P1, and MIR7156. Each is linked with PRR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR5-to-partner and partner-to-PRR5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR5→partner) and Y-score (partner→PRR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTND5P7 →	+0.024	+5.144	<.001	.003	3	2
COAD	NDUFS6P1 →	+0.172	+5.136	<.001	.002	3	2
CESC	MIR7156 →	+0.668	+4.669	<.001	.007	3	2
SKCM	NICN2P →	+0.063	+2.855	<.001	.009	3	2
LIHC	OR8B6P →	+0.043	+5.647	<.001	.004	3	2
BLCA	RNU4-85P →	+0.432	+4.758	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 181 associations by consensus.

Exploration

PRR5 survival (RNA) · tumor vs normal (RNA) · all PRR5 data types