PRR4

Across TCGA patient cohorts, PRR4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR4-associated genes across cancer lineages are Ku80 and SF2. Each is linked with PRR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR4-to-partner and partner-to-PRR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by PRR4-low versus PRR4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR4→partner) and Y-score (partner→PRR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.364	+2.820	.011	.036	1	1
UCEC	SF2 →	+0.218	+2.820	.001	.036	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Ku80 by PRR4 expression — UCEC

Explore this box plot interactively →