PRR4

Across TCGA cell cohorts, PRR4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,833 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PRR4-associated GO terms across cancer lineages are mRNA splice site recognition, Nuclear-transcribed mRNA catabolic process, and Negative regulation of myoblast fusion. Each is linked with PRR4 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRR4-to-partner and partner-to-PRR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by PRR4-low versus PRR4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR4→partner) and Y-score (partner→PRR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	mRNA splice site recognition →	+0.127	+1.083	.001	<.001	3	12
LUNG_NSCLC_LUAD	Nuclear-transcribed mRNA catabolic process →	+0.038	+0.644	<.001	.004	3	10
BONE	Negative regulation of myoblast fusion →	+0.110	+0.990	<.001	<.001	3	10
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.114	+0.915	<.001	<.001	3	10
LARGE_INTESTINE	Microtubule nucleation →	+0.128	+0.759	<.001	.001	3	10
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.101	+0.954	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,833 associations by consensus.

mRNA splice site recognition by PRR4 expression — URINARY_TRACT

Explore this box plot interactively →