Across TCGA patient cohorts, PRR36 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR36-associated genes across cancer lineages are Ku80, p62 Lck ligand, and MEK1. Each is linked with PRR36 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR36-to-partner and partner-to-PRR36 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR36→partner) and Y-score (partner→PRR36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.365	+3.183	.004	.010	3	1
UCEC	p62 Lck ligand →	+0.436	+2.817	.014	.036	3	1
UCEC	MEK1 →	+0.471	+3.169	.018	.020	2	1
UCEC	Cyclin-B1 →	+0.848	+3.169	.005	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

PRR36 survival (RNA) · tumor vs normal (RNA) · all PRR36 data types