PRR35

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRR35 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PRR35-associated genes across cancer lineages are Macrophages and CLP. Each is linked with PRR35 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR35-to-partner and partner-to-PRR35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macrophages grouped by PRR35-low versus PRR35-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR35→partner) and Y-score (partner→PRR35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMacrophages →+0.051+2.851.005.03432
SKCMCLP →+0.116+2.826.014.03621
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Macrophages by PRR35 expression — SKCM

Box plot of Macrophages in PRR35-low vs PRR35-high samples in SKCM.

Explore this box plot interactively →

Exploration