PRR35

Across TCGA cell cohorts, PRR35 RNA expression is significantly associated with the go_rna of many other GO terms, with 604 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRR35-associated GO terms across cancer lineages are Regulation of telomerase RNA localization to Cajal body, Protein-DNA complex assembly, and Protein-DNA complex organization. Each is linked with PRR35 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRR35-to-partner and partner-to-PRR35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomerase RNA localization to Cajal body grouped by PRR35-low versus PRR35-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR35→partner) and Y-score (partner→PRR35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of telomerase RNA localization to Cajal body →	+0.057	+0.133	.001	.005	2	7
BREAST	Protein-DNA complex assembly →	+0.045	+0.055	<.001	.002	3	6
BREAST	Protein-DNA complex organization →	+0.065	+0.101	<.001	.001	3	6
LARGE_INTESTINE	Positive regulation of monoatomic ion transport →	-0.062	-0.039	<.001	.004	3	6
SOFT_TISSUE	Negative regulation of mRNA processing →	+0.061	+0.099	.004	.005	2	6
SOFT_TISSUE	Establishment of RNA localization →	+0.059	+0.098	.005	.009	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 604 associations by consensus.

Regulation of telomerase RNA localization to Cajal body by PRR35 expression — SOFT_TISSUE

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