PRR34

Across TCGA cell cohorts, PRR34 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,941 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRR34-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Transport along microtubule, and Regulation of smoothened signaling pathway. Each is linked with PRR34 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRR34-to-partner and partner-to-PRR34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by PRR34-low versus PRR34-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR34→partner) and Y-score (partner→PRR34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of nucleotide-excision repair →	+0.091	+0.221	<.001	.002	3	9
LUNG_NSCLC_LUSC	Transport along microtubule →	+0.051	+0.221	.007	.004	2	8
OESOPHAGUS	Regulation of smoothened signaling pathway →	+0.048	+0.292	.002	<.001	3	7
LIVER	Regulation of early endosome to late endosome transport →	+0.129	+0.186	.001	.008	2	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription by RNA polymerase III →	+0.162	+0.210	<.001	<.001	3	7
CNS	Regulation of focal adhesion assembly →	+0.067	+0.231	.004	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,941 associations by consensus.

Regulation of nucleotide-excision repair by PRR34 expression — OVARY

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