PRR34-AS1

Across TCGA pan-cancer cohorts, PRR34-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PRR34-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher PRR34-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRR34-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and DLBC show a favorable association.

UVM, BRCA, and LAML are the cancer types where PRR34-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.420	0.769	<.001	130	view →
BRCA	OS	Median	IV	0.781	0.381	.006	38	view →
LAML	DFS	Median	All	0.471	0.666	.004	36	view →
HNSC	DFS	Median	All	0.246	0.440	.001	33	view →
OV	DFS	Tertile	All	0.322	0.429	.004	32	view →
LIHC	OS	Quartile	All	0.348	0.712	.002	31	view →
PAAD	DFS	Tertile	II,III,IV	0.298	0.564	.001	18	view →
DLBC	OS	Quartile	All	0.955	0.631	.021	17	view →
ACC	OS	Quartile	All	0.300	0.796	.021	17	view →
ESCA	OS	Quartile	III,IV	0.736	0.373	.008	12	view →
UCS	OS	Tertile	IV	0.325	0.756	.024	12	view →
BLCA	OS	Quartile	II,III,IV	0.513	0.696	.003	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PRR34-AS1–UVM (DFS)

Open the UVM breakdown →