Across TCGA patient cohorts, PRR32 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR32-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and ERK2. Each is linked with PRR32 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR32-to-partner and partner-to-PRR32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR32→partner) and Y-score (partner→PRR32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.201	-2.000	.046	.030	3	1
UCEC	A-Raf_pS299 →	-0.119	-2.459	.013	.019	3	1
UCEC	ERK2 →	+0.228	+2.115	.003	.017	3	1
UCEC	GAPDH →	+0.535	+2.000	.013	.030	3	1
UCEC	IGFBP2 →	-0.786	-3.169	.002	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.182	-2.321	.007	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

PRR32 survival (RNA) · tumor vs normal (RNA) · all PRR32 data types