Across TCGA patient cohorts, PRR3 mutation is significantly associated with the RNA expression of many other genes, with 913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR3-associated genes across cancer lineages are PIGPP3, SLC20A1P3, and LINC01072. Each is linked with PRR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR3-to-partner and partner-to-PRR3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR3→partner) and Y-score (partner→PRR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PIGPP3 →	+0.240	+5.602	<.001	<.001	3	2
COAD	SLC20A1P3 →	+0.092	+5.917	<.001	.001	3	2
UCEC	LINC01072 →	+0.248	+3.711	<.001	<.001	3	2
CESC	NPBWR2 →	+0.056	+5.010	<.001	.009	3	1
CESC	HMGB4 →	+0.018	+5.306	<.001	.006	3	1
CESC	RNA5SP321 →	+0.386	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 913 associations by consensus.

Exploration

PRR3 survival (RNA) · tumor vs normal (RNA) · all PRR3 data types