PRR29

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRR29 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR29-associated genes across cancer lineages are EGFR_pY1068, ERK2, and MAPK_pT202_Y204. Each is linked with PRR29 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR29-to-partner and partner-to-PRR29 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR29→partner) and Y-score (partner→PRR29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.277-2.459.022.02031
UCECERK2 →+0.192+3.000.039.03631
UCECMAPK_pT202_Y204 →-0.478-3.000.035.03631
UCECPDK1_pS241 →+0.241+3.169.003.01931
UCECShc_pY317 →-0.174-2.459.017.02031
UCECSTAT3_pY705 →-0.421-3.169<.001.01831
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration