PRR29-AS1

Across TCGA pan-cancer cohorts, PRR29-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of PRR29-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where PRR29-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PRR29-AS1 is over-expressed in tumor, although a few such as LUSC and KICH show the opposite, repressed pattern.

LUSC, KICH, and THCA are the cancer types where PRR29-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PRR29-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	III,IV	−0.257	<.001	9	view →
KICH	All	All	−0.116	<.001	7	view →
THCA	Female	All	+0.324	<.001	5	view →
BRCA	All	All	−0.060	<.001	4	view →
UCEC	All	All	−0.283	.014	2	view →
LIHC	All	II,III,IV	+0.018	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

PRR29-AS1–LUSC

Open the LUSC breakdown →