Across TCGA patient cohorts, PRR27 mutation is significantly associated with the RNA expression of many other genes, with 1,024 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR27-associated genes across cancer lineages are OR7E97P, MTCYBP9, and MIR4452. Each is linked with PRR27 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR27-to-partner and partner-to-PRR27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR27→partner) and Y-score (partner→PRR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR7E97P →	+0.035	+5.339	<.001	.003	3	2
LUAD	MTCYBP9 →	+0.316	+4.672	<.001	<.001	3	2
BRCA	MIR4452 →	+0.433	+5.016	<.001	.005	3	2
BRCA	RPL23AP54 →	+0.095	+4.760	<.001	.007	3	2
BRCA	LINC01995 →	+0.216	+5.211	.002	.001	3	2
UCEC	RIC8A →	+0.395	+3.617	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,024 associations by consensus.

Exploration

PRR27 survival (RNA) · tumor vs normal (RNA) · all PRR27 data types