Across TCGA patient cohorts, PRR27 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR27-associated genes across cancer lineages are INPP4B, JNK2, and p62 Lck ligand. Each is linked with PRR27 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR27-to-partner and partner-to-PRR27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR27→partner) and Y-score (partner→PRR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.327	-3.000	.030	.036	3	1
UCEC	JNK2 →	+0.295	+2.834	.001	.034	3	1
UCEC	p62 Lck ligand →	+0.413	+2.179	.006	.034	3	1
UCEC	Annexin-1 →	+0.517	+2.189	.035	.034	3	1
UCEC	XBP1 →	-0.253	-3.446	<.001	.005	3	1
UCEC	ATM →	-0.686	-2.584	.001	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

PRR27 survival (RNA) · tumor vs normal (RNA) · all PRR27 data types