Across TCGA cell cohorts, PRR27 RNA expression is significantly associated with the mutation status of many other genes, with 105 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRR27-associated genes across cancer lineages are VPS16, KLRG2, and ZNF592. Each is linked with PRR27 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR27-to-partner and partner-to-PRR27 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR27→partner) and Y-score (partner→PRR27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	VPS16 →	+3.906	+0.019	.009	<.001	3	2
PANCREAS	KLRG2 →	+4.029	+0.013	.007	<.001	3	2
LIVER	ZNF592 →	+4.459	+0.025	.001	<.001	3	2
LARGE_INTESTINE	ERF →	+3.376	+0.156	.002	<.001	3	2
LARGE_INTESTINE	CAND1 →	+2.054	+0.088	.008	<.001	3	2
SKIN	NBAS →	+2.614	+0.013	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

Exploration

PRR27 survival (RNA) · tumor vs normal (RNA) · all PRR27 data types