PRR23D1

Across TCGA patient cohorts, PRR23D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,066 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRR23D1-associated GO terms across cancer lineages are Positive regulation of proteasomal protein catabolic process, Positive regulation of double-strand break repair via homologous recombination, and Cardiac ventricle development. Each is linked with PRR23D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRR23D1-to-partner and partner-to-PRR23D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal protein catabolic process grouped by PRR23D1-low versus PRR23D1-high in LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23D1→partner) and Y-score (partner→PRR23D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	Positive regulation of proteasomal protein catabolic process →	+0.174	+0.005	<.001	.007	2	4
STAD	Positive regulation of double-strand break repair via homologous recombination →	+0.089	+0.008	<.001	.002	3	3
STAD	Cardiac ventricle development →	+0.059	+0.008	<.001	.002	3	3
STAD	Establishment of cell polarity →	+0.091	+0.008	<.001	.002	3	3
STAD	Obsolete cellular response to extracellular stimulus →	+0.091	+0.009	<.001	<.001	3	3
STAD	Protein depolymerization →	+0.069	+0.005	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,066 associations by consensus.

Positive regulation of proteasomal protein catabolic process by PRR23D1 expression — LUSC

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