PRR23D1

Across TCGA cell cohorts, PRR23D1 RNA expression is significantly associated with the go_rna of many other GO terms, with 532 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRR23D1-associated GO terms across cancer lineages are Negative regulation of testosterone biosynthetic process, Single fertilization, and Mesenchymal cell migration. Each is linked with PRR23D1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRR23D1-to-partner and partner-to-PRR23D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of testosterone biosynthetic process grouped by PRR23D1-low versus PRR23D1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23D1→partner) and Y-score (partner→PRR23D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of testosterone biosynthetic process →	-0.172	-0.033	<.001	.002	3	4
OVARY	Single fertilization →	-0.086	-0.032	<.001	.002	3	3
OVARY	Mesenchymal cell migration →	-0.073	-0.043	.004	.008	3	3
LUNG_NSCLC_LUAD	Amylin receptor signaling pathway →	-1.034	-0.008	<.001	.006	3	3
SOFT_TISSUE	Regulation of heart morphogenesis →	+0.258	+0.056	<.001	.001	3	3
SOFT_TISSUE	Olfactory bulb interneuron differentiation →	+0.405	+0.049	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 532 associations by consensus.

Negative regulation of testosterone biosynthetic process by PRR23D1 expression — SOFT_TISSUE

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