PRR23C

Across TCGA pan-cancer cohorts, PRR23C Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PRR23C data layer compared with 21 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PRR23C Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated PRR23C expression acts as an unfavorable survival marker, although some lineages such as UCEC and SCLC show a favorable association.

UCEC, DLBC, and HNSC are the cancer types where PRR23C Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.629	.018	12	view →
DLBC	OS	Median	II,III,IV	0.118	0.802	.025	6	view →
HNSC	DFS	Median	All	0.182	0.626	.031	6	view →
COAD	DFS	Median	All	0.183	0.696	.006	6	view →
SCLC	DFS	Median	III,IV	1.000	0.229	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PRR23C–UCEC (DFS)

Open the UCEC breakdown →