Across TCGA patient cohorts, PRR23B mutation is significantly associated with the RNA expression of many other genes, with 1,609 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR23B-associated genes across cancer lineages are RPL23AP97, FAM177A1, and RN7SKP261. Each is linked with PRR23B in more than 2 cancer types. Because this analysis shows association rather than direction, both PRR23B-to-partner and partner-to-PRR23B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23B→partner) and Y-score (partner→PRR23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPL23AP97 →	+0.577	+2.594	<.001	<.001	3	3
UCEC	FAM177A1 →	+0.322	+1.662	.002	.004	3	3
LUAD	RN7SKP261 →	+0.250	+3.787	<.001	.007	3	3
SKCM	RPL31P53 →	+0.024	+2.823	<.001	.007	3	3
LUSC	RN7SL332P →	+0.108	+3.297	<.001	.005	3	3
SKCM	CUX2P1 →	+0.023	+2.823	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,609 associations by consensus.

Exploration

PRR23B survival (RNA) · tumor vs normal (RNA) · all PRR23B data types