Across TCGA patient cohorts, PRR23B mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR23B-associated genes across cancer lineages are ATM, N-Cadherin, and JNK2. Each is linked with PRR23B in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR23B-to-partner and partner-to-PRR23B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23B→partner) and Y-score (partner→PRR23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ATM →	-0.390	-2.000	.027	.031	3	2
SKCM	N-Cadherin →	+0.175	+3.169	.045	.018	3	2
UCEC	JNK2 →	+0.244	+1.901	<.001	.028	3	1
UCEC	Ku80 →	+0.189	+1.375	.023	.024	3	1
UCEC	PRAS40_pT246 →	+0.149	+1.375	.013	.024	3	1
UCEC	S6_pS240_S244 →	+0.314	+1.662	.028	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

PRR23B survival (RNA) · tumor vs normal (RNA) · all PRR23B data types