Across TCGA cell cohorts, PRR23B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRR23B-associated genes across cancer lineages are OR56B1, CLEC2A, and RD3L. Each is linked with PRR23B in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR23B-to-partner and partner-to-PRR23B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23B→partner) and Y-score (partner→PRR23B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR56B1 →	+0.034	+4.887	.001	.009	3	2
LUNG_SCLC	CLEC2A →	+0.107	+5.029	<.001	.006	3	1
LUNG_SCLC	RD3L →	+0.032	+5.029	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR52E6 →	+0.141	+4.887	.001	.009	3	1
LARGE_INTESTINE	OR4K1 →	+0.024	+4.415	<.001	.007	3	1
LARGE_INTESTINE	PTCRA →	+0.075	+4.095	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

PRR23B survival (RNA) · tumor vs normal (RNA) · all PRR23B data types