Across TCGA patient cohorts, PRR23A mutation is significantly associated with the RNA expression of many other genes, with 681 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR23A-associated genes across cancer lineages are KIAA1191, NUTF2P8, and MALINC1. Each is linked with PRR23A in more than 2 cancer types. Because this analysis shows association rather than direction, both PRR23A-to-partner and partner-to-PRR23A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23A→partner) and Y-score (partner→PRR23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	KIAA1191 →	+0.472	+3.518	<.001	.002	3	3
UCEC	NUTF2P8 →	+0.140	+2.661	<.001	.006	3	2
SKCM	MALINC1 →	+0.652	+3.214	<.001	.009	3	2
UCEC	COMTD1 →	+0.811	+3.329	.001	.005	3	2
UCEC	PRELID1 →	+0.437	+3.402	.008	.004	3	2
UCEC	TMEM80 →	+0.553	+3.223	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 681 associations by consensus.

Exploration

PRR23A survival (RNA) · tumor vs normal (RNA) · all PRR23A data types