Across TCGA patient cohorts, PRR23A mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR23A-associated genes across cancer lineages are cIAP, AR, and Caveolin-1. Each is linked with PRR23A in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR23A-to-partner and partner-to-PRR23A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR23A→partner) and Y-score (partner→PRR23A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cIAP →	+0.148	+2.196	.040	.034	3	2
LUSC	AR →	-0.176	-2.990	.017	.036	3	1
LUSC	Caveolin-1 →	-0.826	-3.000	.013	.035	3	1
UCEC	Caspase-8 →	-0.260	-2.973	.048	.035	3	1
UCEC	CD20 →	+0.150	+2.827	.029	.035	3	1
LUSC	PDK1_pS241 →	+0.211	+3.009	.004	.019	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

PRR23A survival (RNA) · tumor vs normal (RNA) · all PRR23A data types