Across TCGA patient cohorts, PRR22 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,340 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRR22-associated proteins across cancer lineages are KHSRP, CHAF1A, and FES. Each is linked with PRR22 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRR22-to-partner and partner-to-PRR22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR22→partner) and Y-score (partner→PRR22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KHSRP →	+0.290	+0.656	<.001	<.001	3	5
LSCC	CHAF1A →	+0.646	+0.582	<.001	<.001	3	4
LSCC	FES →	-0.315	-0.572	<.001	<.001	3	4
LSCC	KRI1 →	+0.393	+0.469	<.001	<.001	3	4
UCEC	SLC12A4 →	-0.408	-0.647	<.001	.002	3	3
UCEC	SRRM2_S510 →	+0.592	+0.536	.008	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,340 associations by consensus.

Exploration

PRR22 survival (RNA) · tumor vs normal (RNA) · all PRR22 data types