Across TCGA patient cohorts, PRR22 mutation is significantly associated with the RNA expression of many other genes, with 945 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR22-associated genes across cancer lineages are OR56A7P, RNA5SP486, and MIR4276. Each is linked with PRR22 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR22-to-partner and partner-to-PRR22 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR22→partner) and Y-score (partner→PRR22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR56A7P →	+0.047	+5.038	.002	.009	3	2
LGG	RNA5SP486 →	+0.406	+7.977	<.001	.007	3	2
LGG	MIR4276 →	+0.463	+7.977	<.001	.007	3	2
LUSC	LINC02134 →	+0.169	+5.548	<.001	.004	3	2
SKCM	MIR4472-1 →	+0.263	+5.408	<.001	.002	3	2
UCEC	RNA5SP420 →	+0.607	+2.230	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 945 associations by consensus.

Exploration

PRR22 survival (RNA) · tumor vs normal (RNA) · all PRR22 data types