Across TCGA cell cohorts, PRR22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,938 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible PRR22-associated GO terms across cancer lineages are rRNA metabolic process, Membrane raft localization, and Regulation of transcription by RNA polymerase I. Each is linked with PRR22 in more than 15 cancer types. Because this analysis shows association rather than direction, both PRR22-to-partner and partner-to-PRR22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR22→partner) and Y-score (partner→PRR22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	rRNA metabolic process →	+0.133	+0.975	<.001	<.001	3	16
SOFT_TISSUE	Membrane raft localization →	-0.208	-0.948	<.001	<.001	3	14
BONE	Regulation of transcription by RNA polymerase I →	+0.123	+0.942	<.001	<.001	3	14
BONE	rRNA processing →	+0.129	+0.724	<.001	.008	2	15
BONE	Regulation of double-strand break repair via homologous recombination →	+0.107	+0.790	.001	.002	3	14
LIVER	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.122	+1.207	.002	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,938 associations by consensus.

Exploration

PRR22 survival (RNA) · tumor vs normal (RNA) · all PRR22 data types