PRR20E

Across TCGA patient cohorts, PRR20E RNA expression is significantly associated with the go_rna of many other GO terms, with 120 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PRR20E-associated GO terms across cancer lineages are Regulation of peptidyl-lysine acetylation, Regulation of cellular pH reduction, and Regulation of signaling receptor activity. Each is linked with PRR20E in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR20E-to-partner and partner-to-PRR20E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of peptidyl-lysine acetylation grouped by PRR20E-low versus PRR20E-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR20E→partner) and Y-score (partner→PRR20E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of peptidyl-lysine acetylation →	-0.026	-0.061	.003	<.001	3	1
LAML	Regulation of cellular pH reduction →	-0.064	-0.071	<.001	.006	3	1
KIRC	Regulation of signaling receptor activity →	+0.036	+0.004	<.001	.002	2	1
KIRC	Regulation of translation at synapse →	+0.046	+0.005	<.001	.002	2	1
KIRC	Regulation of reactive oxygen species metabolic process →	+0.054	+0.002	<.001	.006	2	1
KIRC	Regulation of nervous system process →	+0.029	+0.002	.002	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 120 associations by consensus.

Regulation of peptidyl-lysine acetylation by PRR20E expression — LAML

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