Across TCGA patient cohorts, PRR19 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRR19-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and FoxM1. Each is linked with PRR19 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR19-to-partner and partner-to-PRR19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR19→partner) and Y-score (partner→PRR19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.286	-2.584	.014	.011	3	1
UCEC	A-Raf_pS299 →	-0.178	-3.000	.001	.036	3	1
UCEC	FoxM1 →	+0.344	+2.584	.004	.011	3	1
UCEC	INPP4B →	-0.344	-2.571	.022	.011	3	1
UCEC	Ku80 →	+0.246	+2.331	.025	.019	3	1
UCEC	Myosin-IIa →	+0.235	+3.010	.008	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

PRR19 survival (RNA) · tumor vs normal (RNA) · all PRR19 data types