Across TCGA cell cohorts, PRR16 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,606 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRR16-associated GO terms across cancer lineages are Regulation of protein K48-linked ubiquitination, Positive regulation of supramolecular fiber organization, and Regulation of cell-matrix adhesion. Each is linked with PRR16 in more than 11 cancer types. Because this analysis shows association rather than direction, both PRR16-to-partner and partner-to-PRR16 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR16→partner) and Y-score (partner→PRR16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein K48-linked ubiquitination →	+0.135	+2.026	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.103	+2.023	.001	.003	3	12
BONE	Regulation of cell-matrix adhesion →	+0.139	+2.564	<.001	<.001	3	12
BONE	Substrate adhesion-dependent cell spreading →	+0.200	+2.608	<.001	<.001	3	12
BONE	Positive regulation of establishment of T cell polarity →	+0.198	+3.276	<.001	<.001	3	12
LIVER	Maintenance of protein location →	+0.142	+2.453	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,606 associations by consensus.

Exploration

PRR16 survival (RNA) · tumor vs normal (RNA) · all PRR16 data types