Across TCGA cell cohorts, PRR16 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PRR16-associated genes across cancer lineages are RNASE2, OR5T2, and PRAMEF10. Each is linked with PRR16 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR16-to-partner and partner-to-PRR16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR16→partner) and Y-score (partner→PRR16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	RNASE2 →	+0.175	+3.662	<.001	.009	3	1
LUNG_SCLC	OR5T2 →	+0.012	+4.058	<.001	.007	3	1
LUNG_SCLC	PRAMEF10 →	+0.708	+4.058	<.001	.007	3	1
LUNG_SCLC	OR5H2 →	+0.030	+4.058	<.001	.007	3	1
LUNG_SCLC	C10orf62 →	+0.084	+3.669	<.001	.008	3	1
LUNG_SCLC	PRAMEF20 →	+0.300	+4.684	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

PRR16 survival (RNA) · tumor vs normal (RNA) · all PRR16 data types