PRR15

Across TCGA pan-cancer cohorts, PRR15 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated PRR15 data layer compared with 28 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PRR15 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRR15 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where PRR15 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.917	.011	78	view →
PDAC	DFS	Tertile	All	0.648	0.292	<.001	49	view →
LUAD	OS	Median	III,IV	0.252	0.790	.011	17	view →
UCEC	DFS	Quartile	All	1.000	0.795	.008	6	view →
LSCC	DFS	Quartile	II,III,IV	0.562	0.904	.013	4	view →
HNSC	DFS	Quartile	III,IV	0.342	1.000	.021	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PRR15–COAD (DFS)

Open the COAD breakdown →