PRR15

Across TCGA patient cohorts, PRR15 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. CESC shows the largest number of these associations.

The most reproducible PRR15-associated genes across cancer lineages are RPS26P30, PCYT1B-AS1, and RN7SL340P. Each is linked with PRR15 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR15-to-partner and partner-to-PRR15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS26P30 grouped by PRR15-low versus PRR15-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR15→partner) and Y-score (partner→PRR15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPS26P30 →	+0.116	+5.812	<.001	.003	3	1
CESC	PCYT1B-AS1 →	+0.138	+5.969	.005	.002	3	1
CESC	RN7SL340P →	+0.135	+5.306	<.001	.006	3	1
CESC	ARHGAP22-IT1 →	+0.082	+5.201	<.001	.007	3	1
CESC	RNA5SP162 →	+0.801	+5.103	<.001	.008	3	1
CESC	RNU6-579P →	+0.359	+6.342	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

RPS26P30 by PRR15 expression — CESC

Explore this box plot interactively →