PRR15

Across TCGA cell cohorts, PRR15 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRR15-associated genes across cancer lineages are ACTL7A and OR52K1. Each is linked with PRR15 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRR15-to-partner and partner-to-PRR15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTL7A grouped by PRR15-low versus PRR15-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR15→partner) and Y-score (partner→PRR15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACTL7A →	+0.029	+3.823	<.001	.006	3	1
LARGE_INTESTINE	OR52K1 →	+0.015	+4.217	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ACTL7A by PRR15 expression — LARGE_INTESTINE

Explore this box plot interactively →