PRR14

Across TCGA pan-cancer cohorts, PRR14 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated PRR14 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PRR14 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated PRR14 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where PRR14 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.914	0.630	<.001	77	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.367	.003	15	view →
LSCC	OS	Tertile	All	0.669	1.000	.015	14	view →
HNSC	DFS	Median	All	0.985	0.905	.003	14	view →
PDAC	DFS	Median	II,III,IV	0.528	0.304	.008	12	view →
UCEC	OS	Median	II,III,IV	0.638	1.000	.014	4	view →
GBM	OS	Tertile	All	0.769	0.977	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

PRR14–CCRCC (OS)

Open the CCRCC breakdown →