PRR14

Across TCGA patient cohorts, PRR14 protein abundance is significantly associated with the RNA expression of many other genes, with 11,379 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible PRR14-associated genes across cancer lineages are DCN, PLEKHH2, and COX7A1. Each is linked with PRR14 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRR14-to-partner and partner-to-PRR14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRR14 versus DCN in BRCA, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR14→partner) and Y-score (partner→PRR14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DCN →	+0.995	+0.222	.003	.002	3	5
UCEC	PLEKHH2 →	+1.063	+0.250	<.001	<.001	3	5
BRCA	COX7A1 →	+0.939	+0.174	<.001	.003	3	5
CCRCC	CSDC2 →	+1.378	+0.312	.001	<.001	3	5
OV	GNG7 →	+0.746	+0.280	.001	.001	3	5
UCEC	LINC01359 →	+1.060	+0.244	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,379 associations by consensus.

PRR14 vs DCN — BRCA

Explore this scatter interactively →