PRR14

Across TCGA cell cohorts, PRR14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,760 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRR14-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Regulation of chromatin organization, and Positive regulation of intracellular estrogen receptor signaling pathway. Each is linked with PRR14 in more than 10 cancer types. Because this analysis shows association rather than direction, both PRR14-to-partner and partner-to-PRR14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by PRR14-low versus PRR14-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRR14→partner) and Y-score (partner→PRR14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.129	+0.558	.001	<.001	3	11
KIDNEY	Regulation of chromatin organization →	+0.098	+0.635	<.001	.001	3	10
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.145	+0.716	<.001	<.001	3	10
SKIN	Methylglyoxal catabolic process →	+0.140	+0.534	<.001	<.001	3	9
KIDNEY	Positive regulation of macrophage proliferation →	+0.170	+0.600	<.001	<.001	3	9
KIDNEY	Regulation of Golgi inheritance →	+0.121	+0.678	.007	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,760 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by PRR14 expression — LARGE_INTESTINE

Explore this box plot interactively →