Across TCGA pan-cancer cohorts, PRR13P4 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of PRR13P4’s most consistent transcriptional readouts.
The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where PRR13P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PRR13P4 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
LIHC, THCA, and LUSC are the cancer types where PRR13P4 tumor–normal differential expression is most reproducible.